“You need 1 gram of protein per pound of body weight to build muscle”
More protein helps lifters, but gains level off near 1.6 g/kg, about 0.7 g per pound, making 1 g per pound a generous ceiling.
Claim check
Trials show creatine plus lifting adds about a kilogram of lean mass, and kidney filtration shows no significant change, though one common blood test can read higher.
“Creatine is just water weight, and it hurts your kidneys.”
Creatine holds a little water at first, but with lifting it adds real lean mass, and trials show no kidney harm in healthy people.
1.1kg
Extra lean mass when creatine is added to resistance training
Source 11.14kg
Extra lean mass, adults under 50 who lift
Source 20.13mg/dL
Rise in blood creatinine with creatine (a breakdown product, not a sign of damage on its own)
Source 43–5g/day
Daily amount the ISSN says maintains muscle creatine stores
Source 5Our own summary of the sources listed at the bottom of this page.
Every chart is drawn from the published estimates. Bars and intervals show the uncertainty; a dashed line marks no difference.
Pooled differences between creatine and placebo groups with 95% confidence intervals. Lean mass rose with lifting but not without exercise, which is hard to square with a pure water effect.
Sources: 1Nutrition, 2022 2Journal of Strength and Conditioning Research, 2024 3Open Access Journal of Sports Medicine, 2017
A 2026 meta-analysis of randomized trials found a small rise in creatinine but no change in urea; estimated filtration rate also showed no significant difference. Source: Tsiaras and colleagues, Journal of Renal Nutrition.
Point estimates from three meta-analyses; the result for women was not statistically significant. Sources: Delpino 2022, Desai 2024, and Chilibeck 2017.
Sources: 1Nutrition, 2022 2Journal of Strength and Conditioning Research, 2024 3Open Access Journal of Sports Medicine, 2017
The claim
The evidence
A side-by-side summary of the two creatine myths and what randomized trials found. Sources: Delpino 2022, Tsiaras 2026, and the ISSN 2017 position stand.
Written and drawn by go4 with AI assistance (Claude, by Anthropic) after reading these sources, and checked against them. No text or figures were copied. Checked Oct 2026.
More protein helps lifters, but gains level off near 1.6 g/kg, about 0.7 g per pound, making 1 g per pound a generous ceiling.
Hard sets that end close to failure help growth, but actually reaching failure is not required for most people.